The Prostate Health Index (PHI) may be used to determine the probability of prostate cancer in men.
The test begins with the analysis of Prostate-Specific Antigen (PSA). If the concentration is between 2.0 and 10.0 ng/mL, then the reflex test will automatically be performed. If the PSA concentration is between 4.0 and 10.0 ng/mL then the percent free PSA result and prostate health index (PHI) will be reported.
If the PSA concentration is between 2.0 and 4.0 ng/mL, then the percent free PSA result and prostate health index (phi) will not be reported.
Result Interpretation
Result Interpretation
Prostate health index (phi) may be used to determine the probability of prostate cancer on biopsy in men with total prostate-specific antigen (PSA) in the 4 to 10 ng/mL range. Low phi scores are associated with a lower probability of finding prostate cancer on biopsy and higher phi scores are associated with an increased probability of finding prostate cancer on biopsy. The choice of an appropriate phi score to be used in guiding clinical decision-making may vary for each patient and may depend on other clinical factors or on family history of disease. The table below indicates the probability of finding prostate cancer on biopsy when PSA is the in range of 4 to 10 ng/mL and may be used as guidance for interpreting the phi score.
| phi range | Probability of Cancer | 95% confidence interval |
| 0-26.9 | 9.8% | 5.2%-15.4% |
| 27.0-35.9 | 16.8% | 11.3%-22.2% |
| 36.0-54.9 | 33.3% | 26.8%-39.9% |
| 55.0+ | 50.1% | 39.8%-61% |
What is the cost?
If purchased on its own during your appointment, this test costs $108.00 + Tax.
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If you require a specific test that isn’t on our website, we may be able to offer it to you, as long as it’s tested through a blood draw. Please email our support team using the contact form below with details of the required test. It may take a few weeks until we can quote a price for you, but we will do our best.
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