Prostate Health Index (PHI)

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Prostate Health Index (PHI)

The Prostate Health Index (PHI) may be used to determine the probability of prostate cancer in men.

The test begins with the analysis of Prostate-Specific Antigen (PSA). If the concentration is between 2.0 and 10.0 ng/mL, then the reflex test will automatically be performed. If the PSA concentration is between 4.0 and 10.0 ng/mL then the percent free PSA result and prostate health index (PHI) will be reported. 

If the PSA concentration is between 2.0 and 4.0 ng/mL, then the percent free PSA result and prostate health index (phi) will not be reported. 

Result Interpretation

Result Interpretation

Prostate health index (phi) may be used to determine the probability of prostate cancer on biopsy in men with total prostate-specific antigen (PSA) in the 4 to 10 ng/mL range. Low phi scores are associated with a lower probability of finding prostate cancer on biopsy and higher phi scores are associated with an increased probability of finding prostate cancer on biopsy. The choice of an appropriate phi score to be used in guiding clinical decision-making may vary for each patient and may depend on other clinical factors or on family history of disease. The table below indicates the probability of finding prostate cancer on biopsy when PSA is the in range of 4 to 10 ng/mL and may be used as guidance for interpreting the phi score.

phi range Probability of Cancer 95% confidence interval
0-26.9 9.8% 5.2%-15.4%
27.0-35.9 16.8% 11.3%-22.2%
36.0-54.9 33.3% 26.8%-39.9%
55.0+ 50.1% 39.8%-61%


What is the cost?

If purchased on its own during your appointment, this test costs $108.00 + Tax.

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